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Category: Pharmacist

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Pharmacology

Focuses on drug classifications, mechanisms of action, therapeutic uses, side effects, and contraindications.
Includes questions on drugs affecting various body systems and clinical applications.

1 / 10

Which drug is used to treat atrial fibrillation by slowing AV node conduction?

Adenosine

Digoxin

Amiodarone

Propranolol

Digoxin slows conduction through the AV node and increases vagal tone, making it effective in controlling ventricular response in atrial fibrillation.

2 / 10

Which of the following antibiotics is bactericidal?

Tetracycline

Chloramphenicol

Penicillin

Erythromycin

Penicillin is bactericidal as it disrupts bacterial cell wall synthesis, leading to lysis, whereas tetracycline and chloramphenicol are bacteriostatic.

3 / 10

Which drug is the first-line treatment for acute anaphylaxis?

Hydrocortisone

Epinephrine

Diphenhydramine

Salbutamol

Epinephrine acts on alpha and beta receptors to counteract the severe hypotension, bronchospasm, and swelling seen in anaphylaxis.

4 / 10

What is the mechanism of action of sulfonylureas in diabetes?

Increase insulin sensitivity in tissues

Inhibit glucose absorption in the intestine

Stimulate insulin release from pancreatic beta cells

Decrease hepatic glucose production

Sulfonylureas (e.g., glimepiride) block ATP-sensitive K⁺ channels in beta cells, leading to depolarization and insulin release.

5 / 10

Which antiepileptic drug is associated with gingival hyperplasia as a side effect?

Phenytoin

Carbamazepine

Valproate

Lamotrigine

Phenytoin can cause gingival hyperplasia due to its effect on fibroblast activity, leading to excessive gum tissue growth.

6 / 10

What is the primary action of loop diuretics?

Inhibit sodium-potassium exchange in the distal tubule

Inhibit sodium-chloride co-transport in the loop of Henle

Inhibit sodium-potassium-chloride co-transport in the loop of Henle

Inhibit sodium reabsorption in the collecting duct

Loop diuretics (e.g., furosemide) inhibit the Na⁺/K⁺/2Cl⁻ co-transporter in the thick ascending limb of the loop of Henle, causing profound diuresis.

7 / 10

Which of the following is NOT a prodrug?

Enalapril

Lisinopril

Codeine

Levodopa

Lisinopril is an active drug, unlike enalapril (converted to enalaprilat), codeine (converted to morphine), and levodopa (converted to dopamine in the brain).

8 / 10

Which drug is used as the antidote for organophosphate poisoning?

Atropine

Naloxone

Flumazenil

Protamine sulfate

Atropine, an anticholinergic drug, counteracts the effects of excess acetylcholine at muscarinic receptors, which is a hallmark of organophosphate poisoning.

9 / 10

Which of the following is a selective COX-2 inhibitor?

Aspirin

Ibuprofen

Celecoxib

Diclofenac

Celecoxib selectively inhibits cyclooxygenase-2 (COX-2), reducing inflammation while minimizing gastrointestinal side effects associated with non-selective COX inhibitors.

10 / 10

Which receptor is primarily targeted by beta-blockers?

Alpha-adrenergic receptors

Beta-adrenergic receptors

Muscarinic receptors

Nicotinic receptors

Beta-blockers work by inhibiting beta-adrenergic receptors (β1 and β2), reducing heart rate and myocardial contractility, and are used in conditions like hypertension and arrhythmias.

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Human Anatomy and Physiology

Test your knowledge of Human Anatomy and Physiology (HAP) by exploring key topics such as the structure and function of the human body, organ systems, and essential physiological processes. Perfect for competitive exam preparation or refreshing your basics.

1 / 5

Which antiepileptic drug is associated with gingival hyperplasia as a side effect?

Carbamazepine

Valproate

Lamotrigine

Phenytoin

Phenytoin can cause gingival hyperplasia due to its effect on fibroblast activity, leading to excessive gum tissue growth.

2 / 5

Which of the following antibiotics is bactericidal?

Tetracycline

Chloramphenicol

Erythromycin

Penicillin

Penicillin is bactericidal as it disrupts bacterial cell wall synthesis, leading to lysis, whereas tetracycline and chloramphenicol are bacteriostatic.

3 / 5

What is the mechanism of action of sulfonylureas in diabetes?

Decrease hepatic glucose production

Increase insulin sensitivity in tissues

Inhibit glucose absorption in the intestine

Stimulate insulin release from pancreatic beta cells

Sulfonylureas (e.g., glimepiride) block ATP-sensitive K⁺ channels in beta cells, leading to depolarization and insulin release.

4 / 5

Which drug is used to treat atrial fibrillation by slowing AV node conduction?

Adenosine

Digoxin

Amiodarone

Propranolol

Digoxin slows conduction through the AV node and increases vagal tone, making it effective in controlling ventricular response in atrial fibrillation.

5 / 5

Which drug is the first-line treatment for acute anaphylaxis?

Hydrocortisone

Epinephrine

Diphenhydramine

Salbutamol

Epinephrine acts on alpha and beta receptors to counteract the severe hypotension, bronchospasm, and swelling seen in anaphylaxis.

Your score is

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Category: Pharmacist

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