Medicinal Chemistry Notes PDF:

Unit 1

Antihistaminic agents: Histamine, receptors and their distribution in the humanbody, H1–antagonists Diphenhydramine hydrochloride*, Dimenhydrinate, Doxylamines cuccinate, Clemastine fumarate, Diphenylphyraline hydrochloride, Tripelenamine hydrochloride, Chlorcyclizine hydrochloride, Meclizine hydrochloride, Buclizine hydrochloride, Chlorpheniramine maleate, Triprolidine hydrochloride*, Phenidamine tartarate, Promethazine hydrochloride*, Trimeprazine tartrate, Cyproheptadine hydrochloride, Azatidine maleate, Astemizole, Loratadine, Cetirizine, Levocetrazine Cromolyn sodium, H2-antagonists: Cimetidine*, Famotidine, Ranitidin.

Gastric Proton pump inhibitors: Omeprazole, Lansoprazole, Rabeprazole, Pantoprazole, Anti-neoplastic agents:, Alkylating agents: Meclorethamine*, Cyclophosphamide, Melphalan, Chlorambucil, Busulfan, Thiotepa, Antimetabolites: Mercaptopurine*, Thioguanine, Fluorouracil, Floxuridine, Cytarabine, Methotrexate*, Azathioprine, Antibiotics: Dactinomycin, Daunorubicin, Doxorubicin, Bleomycin, Plant products: Etoposide, Vinblastin sulphate, Vincristin sulphate, Miscellaneous: Cisplatin, Mitotane.

Unit 2

Anti-anginal:
Vasodilators: Amyl nitrite, Nitroglycerin*, Pentaerythritol tetranitrate, Isosorbide dinitrite*, Dipyridamole., Calcium channel blockers: Verapamil, Bepridil hydrochloride, Diltiazem hydrochloride, Nifedipine, Amlodipine, Felodipine, Nicardipine, Nimodipine.
Diuretics:
Carbonic anhydrase inhibitors: Acetazolamide*, Methazolamide, Dichlorphenamide., Thiazides: Chlorthiazide*, Hydrochlorothiazide, Hydroflumethiazide, Cyclothiazide,, Loop diuretics: Furosemide*, Bumetanide, Ethacrynic acid., Potassium sparing Diuretics: Spironolactone, Triamterene, Amiloride., Osmotic Diuretics: Mannitol
Anti-hypertensive Agents: Timolol, Captopril, Lisinopril, Enalapril, Benazepril hydrochloride, Quinapril hydrochloride, Methyldopate hydrochloride,* Clonidine hydrochloride, Guanethidine monosulphate, Guanabenz acetate, Sodium nitroprusside, Diazoxide, Minoxidil, Reserpine, Hydralazine hydrochloride.

Unit 3

Anti-arrhythmic Drugs: Quinidine sulphate, Procainamide hydrochloride, Disopyramide phosphate*, Phenytoin sodium, Lidocaine hydrochloride, Tocainide hydrochloride, Mexiletine hydrochloride, Lorcainide hydrochloride, Amiodarone, Sotalol.

Anti-hyperlipidemic agents: Clofibrate, Lovastatin, Cholesteramine and Cholestipol

Coagulant & Anticoagulants: Menadione, Acetomenadione, Warfarin*, Anisindione, clopidogrel

Drugs used in Congestive Heart Failure: Digoxin, Digitoxin, Nesiritide, Bosentan, Tezosentan.

Unit 4

Drugs acting on Endocrine system

Nomenclature, Stereochemistry and metabolism of steroids

Sex hormones: Testosterone, Nandralone, Progestrones, Oestriol, Oestradiol, Oestrione, Diethyl stilbestrol., Drugs for erectile dysfunction: Sildenafil, Tadalafil., Oral contraceptives: Mifepristone, Norgestril, Levonorgestrol, Corticosteroids: Cortisone, Hydrocortisone, Prednisolone, Betamethasone, Dexamethasone, Thyroid and antithyroid drugs: L-Thyroxine, L-Thyronine, Propylthiouracil, Methimazole

Unit 5

Antidiabetic agents:
Insulin and its preparations
Sulfonyl ureas: Tolbutamide*, Chlorpropamide, Glipizide, Glimepiride.
Biguanides: Metformin.
Thiazolidinediones: Pioglitazone, Rosiglitazone
Meglitinides: Repaglinide, Nateglinide.
Glucosidase inhibitors:Acrabose, Voglibose.
Local Anesthetics: SAR of Local anesthetics
Benzoic Acid derivatives: Cocaine, Hexylcaine, Meprylcaine, Cyclomethycaine, Piperocaine.
Lidocaine/Anilide derivatives: Lignocaine, Mepivacaine, Prilocaine, Etidocaine.
Miscellaneous: Phenacaine, Diperodon, Dibucaine.*

Medicinal Chemistry 5th Semester Notes PDF:

Theese notes are designed to provide a comprehensive overview of the subject matter, and are an invaluable resource for anyone studying Medicinal Chemistry.

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Medicinal Chemistry 5th Semester Notes PDF Download

In conclusion, Medicinal Chemistry and ethics are critical aspects of B.Pharmacy. Pharmacy professionals must uphold these values and ethical principles to ensure that they provide the best possible care to their patients and maintain the highest ethical standards in their work. By understanding the importance of Medicinal Chemistry, B.Pharmacy students can become skilled pharmacists who prioritize the well-being of patients and the public.

Medicinal Chemistry 5th semester notes in PDF format are an excellent resource for anyone studying Medicinal Chemistry. They provide a comprehensive overview of the subject matter, and are easily accessible and easy to understand. So if you want to ace your Medicinal Chemistry exams, be sure to check them out!

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